W. W. "Mo" Cleland: a catalytic life.

نویسندگان

  • Debra Dunaway-Mariano
  • Hazel M Holden
  • Frank M Raushel
چکیده

Professor W. Wallace Cleland, the architect of modern steady-state enzyme kinetics, died on March 6, 2013, from injuries sustained in a fall outside of his home. He will be most remembered for giving the enzyme community Ping-Pong kinetics and the invention of dithiothreitol (DTT). He pioneered the utilization of heavy atom isotope effects for the elucidation of the chemical mechanisms of enzyme-catalyzed reactions. His favorite research journal was Biochemistry, in which he published more than 135 papers beginning in 1964 with the disclosure of DTT.

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عنوان ژورنال:
  • Biochemistry

دوره 52 51  شماره 

صفحات  -

تاریخ انتشار 2013